NAD+
Stocked in 500mg, 1000mg at MontanaPep in Great Falls, Montana. Sold for laboratory research use only.
| Size | Catalog no. | Price per vial |
|---|---|---|
| 500mg | NJ500 | $30 |
| 1000mg | NJ1000 | $50 |
Classification
Endogenous coenzyme (a dinucleotide, NOT a peptide)
Structure and chemistry
NAD+ is nicotinamide adenine dinucleotide: two nucleotides — one bearing adenine, the other nicotinamide — joined through a pair of bridging phosphate groups. It is a coenzyme, not a peptide, and contains no amino acids. It cycles between an oxidized form (NAD+) and a reduced form (NADH); the two are chemically distinct and a product should specify which it contains.
What the published research shows
The foundational biochemistry is among the most thoroughly established in all of science, dating to 1906 and underpinning two Nobel Prizes. Controlled human data on intravenous NAD+ administration, by contrast, are scarce.
Mechanism of action
NAD+ is the principal hydride-carrying coenzyme of cellular metabolism, accepting and donating electrons in glycolysis, the citric acid cycle and oxidative phosphorylation. Beyond redox chemistry it is consumed as a substrate by sirtuins, PARPs and CD38 in processes including DNA repair and gene regulation. Cellular NAD+ levels decline with age, which is the basis for interest in raising them.
Development history
NAD+ was not developed; it is a fundamental molecule of cellular metabolism found in all living cells. It was discovered as an unidentified heat-stable factor required for yeast fermentation and characterized over the following three decades.
Current regulatory status
NAD+ is not an FDA-approved drug for any indication. It sits in the dietary supplement and food-ingredient category, where regulatory oversight differs substantially from drug approval. Note also that NAD+ is a different molecule from its precursors — nicotinamide riboside, nicotinamide mononucleotide, niacin and nicotinamide — which have different regulatory statuses and different bodies of human evidence.
Analytical testing
As a coenzyme rather than a peptide, appropriate analysis is small-molecule analytics — HPLC with UV or LC-MS against a certified reference standard. Two points matter particularly: NAD+ is hygroscopic and degrades with moisture and heat, so handling and storage conditions bear directly on real content; and the oxidized (NAD+) and reduced (NADH) forms should be distinguished analytically rather than assumed.
Ordering from Great Falls
MontanaPep, also known as Montana Peptides, is an independently owned supplier based at 715 13th Ave S, Great Falls, Montana. Local pickup is available by arrangement, and we ship to research addresses across Montana including Billings, Missoula, Bozeman, Helena, Butte, Kalispell and Havre. Call (406) 799-0812 or email customerservice@montanapep.com.